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Next Article. Could autologous cord blood stem cell transplantation treat cerebral palsy? Pathology of acute disseminated encephalomyelitis. Abstract Acute disseminated encephalomyelitis ADEM is an acute, monophasic neurologic syndrome that occurs after vaccination against various viruses and after many viral infections and rarely occurs again in the same patient. Citing Articles Here you can find all Crossref-listed publications in which this article is cited. Clinical characteristics and diagnosis of disseminated encephalomyelitis in adults. Bakulin, Yu.
Neurodegeneration and Inflammation Research Group — Nuffield Department of Clinical Neurosciences
Korzhova, A. Kozlova, R.
Konovalov, A. Vasil'ev, L. Askarova, and M.
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Zhurnal nevrologii i psikhiatrii im. Korsakova , , Volume , Number 2, Page DOI: Popular Features. New Releases. Description For several decades the unsolved etiogenetic and therapeutic problems of multiple sclerosis have offered the strongest challenge to research in neu- rology. The hope of decisive theoretical and practical progress increased when an experimental model presenting far-reaching conformity of structural and pathogenetic features was developed, namely chronic re- lapsing experimental allergic encephalomyelitis CREAE.
During the past years, Dr. Lassmann has contributed substantially to the adaptation of this model with the aim of comprehensive evaluation, thoroughly fol- lowing up his own ideas in numerous studies of individual aspects. The new possibility of continuous and detailed investigation of the clinical, morphological and immunological characteristics of temporal phase sequence of autoimmune demyelination has led to many new findings, corrections offormer hypotheses, and, from correlated studies of human multiple sclerosis, a series of important data concerning, for example, early manifestations of demyelination, the range of so-called acute mul- tiple sclerosis and the incidence of remyelination.
Moreover, Dr. Lass- mann has analysed several special problems which became definable in the course of his own studies or in collaboration with other groups, in- cluding the initial distribution of demyelinated foci, the cerebrospinal fluid phenomena and immunological findings in the nervous tissue.
The results of these separate studies also led to a deeper understanding of demyelinating processes.
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